CUSTOM ITEM: Guard Column Starter Set, Bidentate C8, complete with 5 each 2.0 mm ID x 10 mm long cartridges packed with 5 um, 300 A phase and 1 each guard column holder. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40008‑PG1‑3 Cogent Bidentate C8 Guard Column Starter Set provides a complete protection system for analytical HPLC columns, especially when working with large‑pore stationary phases and biomolecule‑compatible methods.
This starter kit includes:
(5) Bidentate C8 guard cartridges
2.0 mm ID × 10 mm length
Packed with 5 µm, 300 Å TYPE‑C™ silica hydride phase
Each cartridge is individually stored in a closeable Delrin™ case, protecting against contamination, drying, and physical damage prior to use.
The included holder is compatible with all Cogent TYPE‑C™ guard cartridges, allowing flexible use across methods.
Designed for 2.1 mm Analytical Columns
This starter kit is optimized for:
2.1 mm ID analytical HPLC columns
LC‑MS applications
Larger‑molecule or biomolecule separations
Proper guard column matching ensures:
Minimal band broadening
Maintained chromatographic efficiency
Consistent method reproducibility
Why Use a Guard Column Starter Kit
Analytical columns are vulnerable to:
Particulates and sample debris
Strongly retained contaminants
Protein or biomolecule fouling
Irreversible phase damage
The 40008‑PG1‑3 starter kit provides a sacrificial protection layer, helping to:
Extend analytical column lifetime
Maintain consistent performance
Reduce maintenance costs
Improve reproducibility
Under typical use, the five included cartridges may protect a column for its full working lifetime, depending on sample cleanliness.
300 Å Pore Size Advantage
The 300 Å pore size is specifically suited for:
Large molecules and biomolecules
Peptides and protein‑related compounds
Complex biological matrices
Applications requiring improved accessibility to stationary phase surface
Compared to 100 Å phases, 300 Å:
Reduces steric exclusion effects
Improves recovery of larger analytes
Enhances consistency in biological separations
Bidentate C8 Guard Phase Advantages
Using the same phase as your analytical column provides:
Matched selectivity and retention behavior
No method re‑validation required
Consistent analyte transfer to the main column
Compared to C18:
Reduces excessive retention
Improves recovery of amine‑containing compounds
Provides alternative selectivity for complex samples
Cogent TYPE‑C™ Technology Benefits
Silica Hydride Surface
Reduced silanol interactions
Improved peak shape for basic compounds
Lower secondary interactions
Faster Equilibration
Reduced method cycle times
Increased throughput
Durability
Resistant to hydrolysis
Long cartridge and column life
Stable under demanding analytical conditions
Typical Applications
LC‑MS and biomolecule analysis
Peptides and protein‑related separations
Pharmaceutical and bioanalytical workflows
Complex biological matrices
Analytical methods requiring column protection
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable